Japan was hit by one of the largest earthquakes ever recorded Friday, spawning a tsunami that hit the the island’s east coast, killing hundreds of people. Many more are missing or injured. The U.S. Geological Survey said the magnitude-8.9 quake was the biggest to hit Japan since record-keeping began in the late 1800s, AP reports.

Below are organizations that mobilize relief efforts for countries hit by disasters.

AMERICAN RED CROSS: Emergency Operation Centers are opened in the affected areas and staffed by the chapters. Donate here.

GLOBALGIVING: Established a fund to disburse donations to organizations providing relief and emergency services to victims of the earthquake and tsunami. Donate here.

SAVE THE CHILDREN: Mobilizing to provide immediate humanitarian relief in the shape of emergency health care and provision of non-food items and shelter. Donate here.

OXFAM USA: Oxfam is poised to respond if disaster strikes vulnerable countries in its path. Donate here.

AMERICARES: Emergency team is on full alert, mobilizing resources and dispatching an emergency response manager to the region. Donate here.

CONVOY OF HOPE: Disaster Response team established connection with in-country partners who have been impacted by the damage and are identifying the needs and areas where Convoy of Hope may be of the greatest assistance. Donate here.

INTERNATIONAL MEDICAL CORPS: Putting together relief teams, as well as supplies, and are in contact with partners in Japan and other affected countries to assess needs and coordinate our activities. Donate here.

SHELTER BOX: The first team is mobilizing to head to Japan and begin the response effort. Donate here.